Potential for using RNA interference as a component of viral disease management programs
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Abstract
Context: The agroecological management of plant virus diseases currently integrates a set of strategies that pursue three fundamental pillars: safety, profitability, and sustainability. In this regard, preventive measures are becoming increasingly important.
Objective: To evaluate the feasibility of incorporating RNAi-based technology into agroecological management programs for plant virus diseases.
Methods: A literature review focusing on the evolution of knowledge and the use of the biotechnological tool RNA interference (RNAi) was conducted.
Results: Topical products using RNAi have demonstrated the ability to efficiently and stably control virus-associated plant diseases based on Spray Induced Gene Silencing.
Conclusions: In the context of ecological and sustainable agriculture, RNAi-based bioproducts can manage virus-associated plant diseases. However, the main challenge is achieving specificity to the target gene in each case. Therefore, knowledge of nucleotide sequences and the use of bioinformatics tools are essential to minimize unwanted effects.
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